Candida Auris: Threat to Health Globally

Paper Info
Page count 1
Word count 352
Read time 2 min
Topic Health
Type Coursework
Language 🇺🇸 US

Introduction

Candida Auris is an emerging Candida species that originated in Japan and was discovered in 2009. This fungus is resistant to antifungal drugs hence they pose threat to health globally. The contagion outbreak causes symptoms of bacterial infection, which are fever and chills that are not reduced by antibiotics drugs. The disease is classified as a nosocomial infection because it can be spread in healthcare settings.

Signs, Symptoms, and Disease Course

The major signs and symptoms of Candida Auris are fever and chills. The fungus can colonize peoples’ bodies without them exhibiting infection symptoms. This is dangerous because one can spread the disease unknowingly. The pathogen enters the body through wounds and invasive pipes such as breathing and feeding tubes, and catheters in a vein. Thereafter, it causes infection in the bloodstream, brain, and heart consequently causing death to the patient.

Virulence Factors and Diagnostic

Candida virulent factors are characterized by their adherence to surfaces, germination, biofilm formation, and proteinase and phospholipase creation. The fungus is more virulent than the Candida albicans strain. This is because it has genes that enable skin colonization and persistence in the environment (Rossato & Colombo, 2018). Candida Auris’s diagnosis is done through the identification of fungal culture phenotypes in the laboratory. However, the most reliable techniques for pathogen identification are matrix-assisted laser desorption ionization-time of flight platforms with C. Auris spectral libraries, T2 magnetic resonance platform with the updated T2Cauris panel, and sequencing of ribosomal DNA (Rybak, 2020). The tests are expensive, thus very few laboratories can afford them.

Treatment, Prevention, and Sequela

Candida Auris is treated using antifungal drugs such as amphoter­icin B, fluconazole, and echinocandins. However, some of C. Auris strains are resistant to amphoter­icin B and fluconazole (Rybak et al., 2020). The Center for Disease Control recommends empiric therapy with echinocandins for infections, which have been persistent for more than 2 months (Rybak et al., 2020). Candida Auris is common in patients who had preexisting medical problems that forced them to stay in nursing homes for a long time. Such diseases include diabetes and blood cancers that weaken the body’s immune system.

References

Rossato, L., & Colombo, A. L. (2018). Candida auris: What have we learned about its mechanisms of pathogenicity? Frontiers in Microbiology, 9, 3081.

Rybak, J.M. (2020). Candida auris is changing the paradigm of antifungal-resistant candida. Web.

Cite this paper

Reference

NerdyBro. (2022, July 14). Candida Auris: Threat to Health Globally. Retrieved from https://nerdybro.com/candida-auris-threat-to-health-globally/

Reference

NerdyBro. (2022, July 14). Candida Auris: Threat to Health Globally. https://nerdybro.com/candida-auris-threat-to-health-globally/

Work Cited

"Candida Auris: Threat to Health Globally." NerdyBro, 14 July 2022, nerdybro.com/candida-auris-threat-to-health-globally/.

References

NerdyBro. (2022) 'Candida Auris: Threat to Health Globally'. 14 July.

References

NerdyBro. 2022. "Candida Auris: Threat to Health Globally." July 14, 2022. https://nerdybro.com/candida-auris-threat-to-health-globally/.

1. NerdyBro. "Candida Auris: Threat to Health Globally." July 14, 2022. https://nerdybro.com/candida-auris-threat-to-health-globally/.


Bibliography


NerdyBro. "Candida Auris: Threat to Health Globally." July 14, 2022. https://nerdybro.com/candida-auris-threat-to-health-globally/.